Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper


Vol 3 Issue 1-2, 2001

Page Number: 83-85

LOCAL ANAESTHETIC ACTIVITY OF ANACYCLUS PYRETHRUM IN LABORATORY ANIMALS

H. VENKATAKRISHNA BHAT, G. M. PANCHAL, G. DEVASANKARIAH, G. GOPALAKRISHNA AND V.K. PATEL

Abstract

The aqueous and alcoholic (2%) extracts of roots of Anacyclus pyrethrum (A. pyrethrum) exhibited in animals local anaesthetic activity of a longer duration than xylocaine (0.2%). In frog plexus anaesthesia guinea pig dermis and rabbit cornea, the herbal root preparation induced anaesthesia in 30– 60 sec. and lasted 1-2 hours longer than xylocaine. This is the first primary study of local anaesthetic activity of this plant.

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