RENUKA YENDE, NIRAJ A. GHANWATE AND ANUSHRI PAJAI
Abstract
Antibiotic-resistant ESKAPE pathogens, including Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacter Spp, are responsible for severe and life-threatening infections. This research study sheds light on the rate of antibiotic resistance exhibited by these pathogens in Amravati (MS) hospitals. The bacteria were isolated from patientsâ biological samples such as urine, pus, and urinary catheters, across multiple hospitals in Amravati. The antimicrobial susceptibility analysis was carried out using the Kirby-Bauer disk-diffusion method, and CLSI guidelines were followed for interpretation. Out of 480 bacterial isolates recovered from 642 clinical specimens, 312 isolates (65%) were identified as ESKAPE pathogens. The most frequently isolated ESKAPE pathogens were E. faecium, S. aureus, and P. aeruginosa, representing 21% of all ESKAPE members, followed by Klebsiella pneumoniae, which accounted for 16%. E. coli was the third most frequently identified pathogen, accounting for 15% of cases, followed by A. baumannii at 6%. The prevalence of ESKAPE isolates in the Amravati (MS) region is alarming. It is crucial to take action to prevent the further spread of these deadly bacteria and protect the health and well-being of our communities.