N.M.R. Suarni, A.A.S.A. Sukmaningsih, N.N. Wirasiti, N.W. Sudatri and A.M. Deshmukh
Abstract
Research on the potential of fermented juwet fruit on histopathology of the seminiferous tubules and testosterone hormone leves of alloxan-induced diabetic rats has been done. The design used in this study was a completely randomized design (CRD) with 4 treatments and each treatment consisted of 5 replicates. The treatment lasted for one month, each food treatment tested was as follows: K- as negative control (given feed and drink only), K+ (positive control) (given alloxan dose 150 mg/kg BW), P1 (given alloxan dose 150 mg/kg BW and fermented juwet fruit equivalent 1800 mg/kg BW), and P2 (given alloxan dose 150 mg/kg BW and glibencelamid 0.8 mg/kg BW). Parameters observed were blood sugar levels, testosterone levels and testicular histopathology. The data were analyzed using One Way Anova test at 95% confidence level (á = 0.05). The fermented juet fruit drink has the potential to improve testosterone hormone levels and testicular histopathology of alloxan-induced diabetic male white rats.