T. Durgadevi, K. Devika, G. Anburaj and C. Thillaiyadi Valliammai
Abstract
The anti-cancer characteristics of Tecoma stans leaf and root extract are described in this work. Initially, methanol was used to extract the crude extract from the dried leaves and roots of Tecoma stans. After that, the extract was examined using FTIR, UV-Visible, and HPLC spectroscopy. The extract was then tested using an in-silico method for molecular docking and compared to Paclitaxel (controller of MCF-7) for its antioxidant and anti-cancer activities on the MCF-7 human breast cancer cell line. Tecoma stans roots and leaf extract included chemical substances that showed different effects on the 6QGK and 4AGC proteins, which are known to affect the survival of tumor cells. Tecoma stans leaf and root extracts were shown to have promise anti-cancer action, with the root extract having somewhat greater potential.