EPIDEMIOLOGICAL SURVEY AND PCR BASED DETECTION OF MUTATION FOR BREAST CANCER IN WEST BENGAL, INDIAARPITA CHATTERJEE AND GOPESWAR MUKHERJEE
Carcinoma breast was the most prevalent malignant condition among women world-wide. Present investigation on the incidence pattern of breast cancer in rural population of West Bengal revealed that among 3219 malignant cases 39.05% showed breast carcinoma including 99.20% females and 0.79% males. Cancer frequency was moderate during 2004 to 2006, but it increased drastically from 2007 and reached maximum peak (28.00%) in 2009. Carcinoma breast was most prevalent in group O (32.86%) and in particularly middle age group (39.46% in 31-40 years age). A PCR based molecular approach was used to identify the mutation of BRCA2 genes and in very few cases (0.8%) BRCA2 999del5 mutation was detected.
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