Ecology, Environment and Conservation Paper

Vol.09, Issue 04, 2003; Page No.(417-421)

THE INTERACTIONS OF SODIURNDODECYLSULPHATE (SOS) WITH RAT LIVER MITOCHONDRIA

Bragadin Marcantoniol, Gallo Michele' and Manente Sabrina

Abstract

In a previous paper it has been proposed that sodium dodecylsulphate (SDS) is an uncoupler (or protonophore) of the oxidative phosphorylation. In the present work we give evidences that the enhancement of proton conductivity by SDS is only a particular case of a more general behaviour of SDS which, like many other detergents, induces enhancement of permeability for all ions.This is a detergent effect due to the interaction of SDS with the hydrophobic chain of the membrane phospholipidic bilayer.The detergent effect is also responsible for the already observed respiratory chain inhibition.

Enter your contact information below to receive full paper.
Your Name :
Email:
Phone:
City:
Cost of Full Paper: Rs.75 for Indian Nationals or $20 (USD) for international subscribers.
By clicking on Request Paper you Agree to pay the above mentioned cost per paper.