BIOSYNTHESIS OF SILVER NANOPARTICLES FROM PENICILLIUMSPS AND THEIR POTENTIAL ANTIOXIDANT ACTIVITYTriveni Ashok Naik and N. MallikarjunAbstract Nanotechnology is a field of science that involves the production of particles with at least one dimensionless than 100 nm. These nanoparticles have found various applications in the field of biomedicine, diagnostic,antimicrobial and anticancer agents etc. The present investigation focuses on the development of economicaland eco-friendly methods for the biosynthesis of Silver Nanoparticles using cell free extract of Penicillium sps. The production of nanoparticles was monitored by scanning through UV Visible Spectrophotometer inthe range of 300-70 nm. Size and shape of nanoparticles were determined by Scanning Electron Microscope(SEM) while the elemental composition was studied by Energy- dispersive X-ray spectroscopy (EDX). Thepresence of various functional groups that might have contributed for stability of silver nanoparticles wasdetermined by Fourier transform infrared spectroscopy (FTIR). Antioxidant activities of silver nanoparticleswere studied by 2,2- diphenylpicrylhydrazyl (DPPH) scavenging, Hydrogen peroxide (H2O2) radicalscavenging and Reducing Power Assay (RPA). The nanoparticles showed dose dependent increase inantioxidant activities with IC50 value of 314.47+4.96 μg/ml and 317.34 + 4.40 μg/ml respectively for DPPHscavenging and H2O2 radical scavenging activity. |