RATIO DERIVATIVE SPECTROPHOTOMETRIC MONITORING AND PHYTOREMEDIATION OF PANTOPRAZOLESOMA MUKHERJEE, SUPARNA DHAR, SUBHANKAR PATHAK AND MONAMI HAQUEAbstract Recently much attention has been placed to identify the presence of emerging contaminants with special reference to pharmaceutical wastes by the development of specific techniques for detection and monitoring of environmental pollutants at the trace level. The present work aims to investigate the application of a non-destructive, selective and less expensive ratio derivative spectrophotometric method for the monitoring of pantoprazole present in the pharmaceutical binary mixture and wastewater without their prior separation. The linear calibration curve was obtained in the concentration range of 1.0-75.0 ppm for pantoprazole (r2 = 0.994). It was found that significant amounts of pantoprazole can be recovered from laboratory prepared binary mixtures (98.73 %, 100.69 % and 103.46 %), distilled water (98.90 %, 100.13 % and 94.57 %) and wastewater (103.60 %, 98.38 % and 104.73 %) via spike method with known concentrations (40.0 ppm, 50.0 ppm and 60.0 ppm respectively) of pharmaceuticals viz. omeprazole and pantoprazole. Interestingly, selected macrophytes (water hyacinth and water lettuce) were capable to remove pantoprazole (~60 %) from waste water samples. |