BIOACTIVE CONSTITUENTS FROM BARK OF PELTOPHORUMPTEROCARPUMBAKER EX K. HEYNEBOSKEY PANCHOLI, SHWETA GUPTA AND BHOOPENDRA K. VERMAAbstract In vitro antimicrobial and antioxidant activities of sequential bark extracts of Peltophorumpterocarpum Baker ex K. Heyne,was tested against four Gram negative, two Gram-positive bacteria and fivefungal isolates. Antioxidant profile was investigated using 2, 2-Diphenyl-1-picryl-hydrazyl and reductioncapability by ferric ion reducing antioxidant potentials method. Bark ethyl acetate extract showed significantactivity against B. subtilis and P. aruginosa (IZ 18.33 ± 0.33 mm and 18.33 ± 0.57 mm with MIC of 62.5 and31.25 μg/ml, respectively) similarly, higher antioxidant potentials with lower IC50value (5 μg/ml; %inhibition of 97.08 at 80 μg/ml), whereas in FRAP method, methanol extract (1463.33 ± 3.33 AAE/mg dwantioxidant potential) show better activity. Further, GC-MS analysis of the ethyl acetate extract confirmed33 compounds. The main identified constituent was 1,2-benzenedicarboxylic acid, bis(2-ethylhexyl) esterwith 48.9% availability. |