THE THERAPEUTIC ROLE OF ALCOHOLIC EXTRACT OF BLACK TEA (CAMELLIA SINENSIS) AGAINST INFECTION WITH STAPHYLOCOCCUS AUREUSAseel J. Mohammad and May T. FlayyihAbstract The present study investigated the antibacterial activity of alcoholic extracts of black tea (Camellia sinensis) leaves on Staphylococcus aureus isolated from skin infection, The agar-well diffusion method was used in the concentrations 150, 250, 350 and 450 mg/ml respectively. That results shows the minimum inhibitory concentration (MIC) of black tea alcohol extract was 150mg/ml with inhibition zone of 19 mm, on the other hand MIC vancomycin against S. aureus was ï³ 64 ïg/ml. The results obtained from the gene expression of Collagen -Binding Adhesion (CBA), showed there was significant induction of the expression in the groups treated with vancomycinin compared with black tea and the highest induction in expression of Collagen -Binding Adhesion (CBA) gene was at Sub MIC concentration of vancomicin (32 ïg/ml) due to the activity of black tea as antibacterial has changed the resistance of S. aureus. |