NICKEL ESSENTIALITY, TOXICITY AND THE MECHANISM OF TOXICITY IN ANIMALRAJ NARAYAN ROYAbstract Nickel is one of the prevalent heavy metal pollutants. The sources of this pollutant are both natural as well as anthropogenic. The ongoing increase of the modern technology is gradually increasing the demand for nickel-containing product. The use of nickel in modern technology is gradually increasing that result in hastened consumption of nickel-containing product. Nickel compounds contaminate our environment during its manufacturing as well as its usage. Their rapid accumulation in different locations of the earth is hazardous. Human society is ultimate facing various adverse effects of nickel toxicity along with all other creatures on the earth. Though, as a micronutrient nickel is important for normal functioning of the animal system but at the elevated concentrations it causes various adverse effects. Through this review article efforts are being made for an analysis of the existing situation related to essentiality, effect and mechanism of nickel toxicity on animals. The investigation at the current scenario is extremely crucial for the realization of the extent of the crisis linked to nickel as an environmental toxicant to accelerate awareness and search for remedy. |