Pollution Research Paper

Vol 39, Feb Suppl. Issue, 2020; Page No.(139-141)

ACUTE INHALATION OF PASSIVE SMOKING ON LUNG OF ALBINO RAT AND AMELIORATIVE ROLE OF AMLA (PHYLLANTHUS EMBLICA)

GULSHBA, ASHA AGARWAL, RAFAT KHAN1 AND B.S. SHARMA

Abstract

In the present study, alteration due to passive smoking of beedi(local Indian cigarette) and supplementation of aqueous extract of amla has been observed in BAL fluid in albino rats. The experiment was conducted on15 albino rats with weighing 90-120g. The albino rats were divided into 3 groups randomly A, B & C. Group A consist of 5 albino rats which are unexposed. Group B consist 5 albino rats which are exposed to passive smoking of 4-beedi for 1hour per day with time interval of 5 min for 28 days. Group C also consist of 5 albino rats which are exposed to passive smoking of 4-beedi along with supplementation of aqueous extract of amla (200 mg/kg b.wt.) for 28 days. BAL fluid counts declined after supplementation of aqueous extract of amla in comparison to beedi smoke exposed to both the sexes due to antioxidant defense mechanism.

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