Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 10, Issue 4, 2008; Page No.(851-854 )

PERSPECTIVES AND APPLICATIONS OF ANTICANCER ENZYME L-ASPARAGINASE

M. MUTHUSIVARAMAPANDIAN, S. ARRIVUKKARASAN, R. ARAVINDAN AND T. VIRUTHAGIRI

Abstract

Cancer, an incurable disease that causes about 22.8% of all deaths remains as a challenging one for the scientists. It is very obvious that we were in the critic position to search for new drugs that have very low side effects with very high activity against cancerous cells. In such an emergency we were supposed to turn over to the natural drugs, the Biomolecules especially the enzymes for curing such drastic diseases. LAsparaginase is a therapeutic enzyme against the Acute Lymphoblastic Leukemia (ALL) and has been produced from various sources that could be used as a drug against ALL after proper modification or immobilization. The quench for Eukaryotic microorganisms that may produce minimal side effects with high activity could yield enzyme to our expectations.

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