ANTIBACTERIAL MECHANISM OF TIO2 NANOPARTICLES AND OPTIMIZE THE PARAMETERS TO MAXIMIZE THE ANTIBACTERIAL BEHAVIOR OF TIO2 COATED SURFACEImtiaz Ahmed Shozib, Azlan Ahmad, Ahmad Majdi Abdul-Rani, Nuzhat Tasnim and Iqbal Taufiqurrahman
This paper gives a brief description of the antibacterial activity of TiO2 nanoparticles along with the antibacterial mechanisms. The killing mechanism of bacteria and the reactions behind them have also been shown. An optimization was carried out to maximize the antibacterial activity using Central Composite Design (CCD) by employing response surface methodology. There are some dependent factors which are responsible for antibacterial activity of coated surface. Three different design factors i.e., the concentration of TiO2 nanoparticles in the plating bath solution, water contact angle of the coated surface and the total surface energy of the substrate surface were selected as the process parameters. Among them the concentration of TiO2 nanoparticles in coating bath solution plays an important role for the antibacterial behavior. By optimizing these three parameters, the surface energy of electron donor component (ï§â) was taken as a response factor. The greater value of (ï§â) shows the highest antibacterial behaviour. The main aim of this optimization is to enhance the surface energy of electron donor component (ï§â) of the coated surface in order to obtain the best protection from bacteria.