Ecology, Environment and Conservation Paper

Vol 25, Issue 3 2019; Page No.(1319-1323)

FABRICATION AND FTIR BASED CHARACTERIZATION OF VITIS VINIFERA LOADED POLYMERIC NANOPARTICLES

Monika Sharma, Ritu Kumari Singh and Chandra Kant Sharma

Abstract

Nanotechnology is a growing subject in the field of science and technology research. Nanoparticles are the most common approach for the drug delivery system now days. Nanoparticles can be prepared by various agents but most safer and non toxic agents are biodegradable polymers. We have used Poly (lacttide- coglycolides) (PLGA) for the fabrication of Vitis vinifera loaded polymeric nanoparticles (VV-PNPs) because it is biodegradable and biocompatible, target specific, non toxic, easy to formulate and cheaper than others. VV-PNPs was fabricated by multiple emulsion solvent evaporation method. Characterization was done by using fourier transform infrared spectroscopy (FTIR). The FTIR for different concentration of V. vinifera aqueous extracts that is 25, 50, 75 and 100 mg is obtained in the range of 1000 cm-1 to 3000 cm-. Efficient capping, stabilization properties of V. vinifera loaded polymeric nanoparticles were revealed by FTIR analysis. Due to its nature of stability, antioxidant property and antimicrobial properties V. vinifera loaded nanoparticles can be further use for biomedical applications.

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