Ecology, Environment and Conservation Paper

ANTITUMOR ACTIVITIES ON HALIMEDA OPUNTIA, HALYMENIA DURVILLAEI, PADINA AUSTRALIS, AND LAURENCIA PAPPILOSA MARINE ALGAE FROM NAIN ISLAND WATERS

Kurniati Kemer, Desy M.H. Mantiri, Esther D. Angkouw, Khristin I.F. Kondoy and Alfred Kase

Abstract

The waters of Nain Island in North Sulawesi has abundant aquatic resources including marine algae. The presence of these resources in the inter tidal zone is highly important, because their chemicals content are beneficial as raw materials in food industry, cosmetics, pharmacy, and so forth. Various researches have been done in order to use of these biological richness sustain ably. Therefore, this study aims to find out anti tumor activities on some algae species found in Nain Island waters. Types of algae to be tested were Halimeda opuntia, Halymenia durvillaei, Padina australis and Laurencia papillosa. Antitumor activity test wasperformed by MTT method [3, (4,5-dimethylthiazol-2yl) -2,5-diphenyltetrazolium bromide]. The tumorcells used were HeLa phasage 30 tumor cells. The results showed that Halimeda opuntia of methanol extracthad cytotoxic activity and was categorized as an active antitumor.