CORRELATION BETWEEN REACTIVE OXYGEN SPECIES WITH NOISE INDUCED HEARING LOSS IN AUTOMOTIVE VOCATIONAL SCHOOL STUDENTVERA MELYANI, NYILO PURNAMI, RIZKA FATHONI PERDANA,DHANY ARIFIANTO AND AINUN NADIROH
Learning process of automotive vocational high school students has a large portion in using practicum machines, that can raise noise and threatens the hearing of students. Noise causes hearing loss known as noise induced hearing loss (NIHL), and it can be permanent, so prevention efforts are very important. Noise exposure that exceeds the threshold results in mechanical damage and metabolic disorders causing changes in calcium homeostasis, stress oxidative cell and increase in the production of free radical known as Reactive Oxygen Species (ROS). This study was observational analytic research with cross sectional design and was held at ORL-HNS OPD of Neurology Division and Installation of Clinical Pathology. There were 46 students with the age 0 range of 17-20 years, the largest group with age range of 17-18 years (78.26%), followed by the age range of 19-20 years (21.74%). Most of the students did not get hearing complaints (91.3%), while students with hearing complaints (8.7%). The measurement of ROS levels with NIHL obtained a minimum value of 3.00 ng/mL and a maximum value of 9.70 ng/mL and the ROS level with non NIHL obtained a minimum value of 0.86 ng/mL and a maximum value of 2.81 ng/mL. All students inthis study had normal PTA values (100%). Audiometry examination in the study found 31 students with NIHL (67.39%) and 15 students (32.61%) with non NIHL. The measuring of practicum machine, students were exposed to noise machines for 9 hours, obtained 3 types of machines which caused noise above the specified limits, namely the compressor engine with (84.8 -102.8 dB), iron cutting machine (81.9- 93.5 dB) and practicum car (88 dB). The Mann-Whitney test showed significant results between ROS levels and NIHL (p <0.05). There was a correlation between ROS levels and NIHL in automotive engineering vocational school students. ROS levels in students with NIHL were higher than ROS levels in students with non NIHL.
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