Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

A STUDY : THE EFFECT OF THYME ON GLUCOSE AND LIPID PROFILE IN ALBINO MALE RATS

MURTADHA GH. JASIM

Abstract

The increase in the use of thyme in Iraq and in neighboring countries, which may be result in serious side effects necessitate the demand for testing different concentrations of thyme extract (500,750,1000) mg/kg of body weight on rats to be given either by injection or feeding grinded dried thyme leaves added to pellets (50,100,150) g /kg of pellet in of different periods, (10,20,30) days for injection and feeding 2 times weekly. Thyme effects on Glucose and Lipids profile (Cholesterol, Triglycerides and HDL) were measured. statistical analysis showed significance decrease difference (P≤0.05) in level of glucose and increase in level of lipid profile (mg / dL) in rats treated with 1000 mg of thyme /kg of body weight and 150 g/kg of pellet in 10 days, in 20 days thyme cause highly significance decrease difference (P≤0.01) in level of glucose and increase in level of lipid profile (mg / dL) in rats treated with thyme by (750,1000) mg/kg of body weight and (100,150) g/kg of pellet and in 30 days thyme cause highly significance decrease difference (P≤0.001) in in level of glucose and increase in level of lipid profile (mg/dL) in rats treated with thyme by (500-750–1000) mg/kg of body weight comparing with the negative and positive controls and (50-100–150) g/kg of pellet comparing with the negative control for feeding.