ORGANIC FLAME RETARDANT INDUCED OXIDATIVE STRESS IN VARIOUS ORGANS OF FRESHWATER FISH CHANNA PUNCTATUSPRINCE SHARMA, POOJA CHADHA AND MANDEEP KAUR
Organo bromide flame retardants have been incorporated into a variety of consumer products including electrical equipments and furniture. Tetrabromobisphenol A (TBBPA) is one of the most widely consumed organic flame retardant. It can leach into the environment and produce adverse effects on ecosystem and aquatic organisms. The present study was conducted to investigate the oxidative stress caused by TBBPA exposure to fresh water fish Channa punctatus. Fish were exposed to 5.09 mg/L (1/2 of LC50) and 2.54 mg/L (1/4 of LC50) of blood, liver and gill of TBBPA along with positive control (acetone) and negative control (water) for 96 hours. Samples were collected after 24, 48, 72 and 96 h post exposure. Results of the study showed a significant increase in malondialdehyde (MDA) levels in all the three tissues. Effect of duration was also found to be significant. In conclusion, TBBPA was found to induce oxidative stress in all the tissues of fish and such findings would provide useful information of potential ecological effects of TBBPA contamination in the environment.
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