COMPARISON OF THE PROTECTIVE EFFECT AND ANTI-DIABETIC AND ANTI-PAIN OF TWO SPECIES OF MEDICINAL HERBS OF PLANTAGINACEAE AND COMPOSITAEA. Hsanvand, M. Rezaei , A. Loni1 and V. Yakhchi
Diabetes is a common disease that can occur at various ages and cause many complications. Based on the anti-diabetic and anti-pain effects of Plantago lanceolata L. and Taraxacum officinale L., the present study evaluated the anti-pain effect of their oral administration in diabetic rats. Using streptozotocin, the present study created similar conditions with human diabetics among the rats in the lab. Then, the effect of hydroalcohol leaf extracts of P. lanceolata and T. officinale were compared employing behavioral tests. The rats were divided into four groups (control, false control, group receiving P. lanceolata and group receiving T. officinale). The treatment with P. lanceolata reduced the scores of pain of formalin test significantly compared with the diabetic group. In addition, treatment with P. lanceolata had significant difference during taking out the tail out of water compared with the diabetic group. The administration of P. lanceolata to diabetic rats affected their pain threshold and reduced their pain significantly; therefore, it is a potential new pain treatment.
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