Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 20, Issue 1, 2018; Page No.(113-119)

ANTIBACTERIAL ACTIVITY TEST OF DIPHENYLTIN(IV) DIBENZOATE AND TRIPHENYLTIN(IV) BENZOATE COMPOUNDS AGAINST BACILLUS SUBSTILIS AND PSEUDOMONAS AERUGINOSA

S. HADI, E. HERMAWATI, NOVIANY, T. SUHARTATI1 AND YANDRI

Abstract

The antibacterial activity test of 2 organotin (IV) compounds, Diphenyltin (IV) dibenzoate (2) and Triphenyltin (IV) benzoate (4) which were prepared by the reaction of Diphenyltin (IV) dihydroxide and triphenyltin (IV) hydroxide with benzoic acid has been pereformed. These compounds were characterized by 1H and 13C NMR, IR, UV-Vis spectroscopies and also based on the microanalytical data. The results of antibacterial activity by diffusion method against Pseudomonas aeruginosa and Bacillus subtilis showed that both compounds werre active at concentration of 200 ppm, which are about 3.89x 10-4 M for 2 and 4.47x10-4 M for 4, while the chloramphenicol, as control postive, at the same concentration 200 ppm ((6.1894 x 10-4 M), gave inhibition with halozone was bigger. This result indicated that both compounds have potential to be used as antibacterial substances.

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