EFFICACY OF LACTOBACILLUS PLANTARUM TO INHIBIT THE GROWTH OF AEROBIC BACTREIAL BURN WOUND PATHOGENSNEMADE SNEHAL, MISHRA SHWETA AND M. MUSADDIQ
Burns are amongst the most devastating of all injuries with out comes spanning the spectrum from physical impairment and disabilities to emotional and mental consequences Infection in burn patient is leading cause of morbidity and mortality and continue to be one of the most challenging concern for the burn team. Alongwith host factor contamination by endogenous and exogenous sources increases the risk. Considering the changing epidemiology, high rate of infection, the problem of drug resistance in common pathogenic microorganisms, the present study was planned to determine the bacterial profile of burn wound with its antibiogram study. These days bacterial resistance has become a major cause for the management of burn wound infections. Use of different combinations of antibiotics has shown the possible synergistic effect in the recovery of severe drug resistant infections. Hence, it has led many investigators to search for new drug therapy. However, indiscriminate using of antibiotics has induced abnormalities on the resident normal flora of gastrointestinal tract and led a major problem at digestibility level in the children. Because of this several workers has reported the effect of antibiotics with other bacteriostatic agents. Hence, with the view to minimize the indiscriminate use of antibiotics and to incorporate the bacteriostatic agent in the therapy for the management of burn wound infections, the present investigation has been carried out to evaluate the inhibitory potential of Lactobacillus plantarum against different burn wound associated bacterial isolates. The results revealed the utility of L. plantarum and its derivatives to combat aerobic bacterial burn wound pathogens.
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