SEASONAL VARIATIONS IN ANTIBACTERIAL AND ANTIFUNGAL ACTIVITY OF EXCOECARIA AGALLOCHAL.A. YERAGI AND V.D. MENDHULKAR
Excoecaria agallocha L. is a small tree found extensively in the mangrove forests around the Mumbai coastal line. The plant belongs to the family Euphorbiaceae and it posses poisonous chemical constituents with medicinal properties. In present study antibacterial and antifungal efficacy of Excoecaria agallocha was studied in different seasonal conditions. The effect was assessed on two bacterial forms (Escherichia coli and Klebsiella pneumoniae) and two fungal forms (Aspergillus flavus and Phytophthora infestans). Antibacterial analysis indicated that the methanolic extract of summer and winter season was effective for Escherichia coli with 10.5 ± 0.577 inhibition. For bark extract, the highest inhibition activity was reported in summer and winter season and it was 7.00 ± 00. For Klebsiella pneumoniae, the highest inhibition activity was reported for methanolic leaf extract of rainy season and it was 11 ± 1.083 cm. For bark extract, the highest inhibition activity reported in summer season was 8.5 ± 0.386 cm. In case of P. infestans, highest inhibition activity reported for methanolic 10 percent leaf extract of rainy season sample and it was 7.5 ± 0.5cm. Overall, the highest activity was reported against P. infestans in all the latex extract samples and the lowest was in the bark of winter extract. For A. flavus, the highest inhibition activity was reported for methanolic leaf extract of rainy season and it was 8.25 ± 1.5 cm and for root extract, the highest inhibition activity was reported in summer season was 7.5 ± 0.577 cm. For bark extract, the highest inhibition activity was reported in rainy season (8.25 ± 0.5 cm). Overall leaf and bark extracts of rainy season showed highest activity against A. flavus which was 8.25 cm. however the highest inhibition was studied in samples dose not exceed to the inhibition limit of standard flucanozole sample which was used for the comparison. Our observations indicates that the samples in methanolic extracts of E. agallocha plant parts are effective against the proliferation of studied bacterial and fungal organisms
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