Pollution Research Paper

PROTECTIVE EFFECT OF VITAMINS ON LEAD INDUCED CHANGES IN OVARY OF SWISS MICE

NAZERA QURESHI, RAGINI SHARMA, SHEETAL MOGRA AND RAZIA BANU

Abstract

Lead has a long evironmental persistence and never losses its toxic potential. Sources of lead may be natural, as it is found in the earths crust and thus enters the food and water supply. Lead affects the reproductive system of Swiss mice. In the present study, toxic effects of lead acetate are observed on the histopathology of ovaries studied after administration of lead acetate to the Swiss mice. Along with this, the therapeutic effect of vitamin C + E on lead acetate induced toxicity has also been investigated. Treated animals show damaging pattern in histology of various component of ovary. Supplementation of vitamin C + E reduces the toxic effect of lead. In the vitamin treated groups along with the lead acetate, the ovaries preserved all components. We conclude that vitamins supplementation found to be more effective in the present study.