Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 16, Issue 1, 2014; Page No.(81-83)

PHYTOCHEMICAL AND ANTIINFLAMMATORY STUDIES OF STEM BARK EXTRACT OF DELONIX ELATA

T. RAGA SUDHAA AND B.GANGA RAO

Abstract

Delonix elata (Fabaceae) is an ornamental and medicinal tree found in Africa and Asia. The methanolic extract of the stem bark of Delonix elata was screened for anti-inflammatory activity in carrageenan-induced rat paw oedema at the dose levels of 100, 200 and 400mg/kg was compared with the standard drug ibuprofen. The extract produced significant and dose dependent inhibition of carrageenaninduced paw oedema. The results were found to be significant (P<0.001) when compared to control. Preliminary phytochemical analysis of Delonix elata indicates the presence of triterpinoids, flavonoids and tannins. Further studies may reveal the exact mechanism of action and phytochemical constituents responsible for anti-inflammatory activity

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