Ecology, Environment and Conservation Paper

PROTECTIVE EFFECT OF TINOSPORA CORDIFOLIA ON SO2 INDUCED SERUM IMMUNOGLOBULIN ALTERATIONS IN ALBINO RAT

Asha Agarwal, Preeti Kumari and Madhuri Yadav

Abstract

The present study is designed to evaluate the protective effect of Tinospora cordifolia (Gelloy) on serum immunoglobulins viz. IgG, IgM and IgA after exposure to SO2 gas (80ppm, 1hr/day) for 30 and 60 days. The results of the present study shows a decrease in the immunoglobulins after 30 and 60 days exposure to SO2 gas. However, SO2 induced serum immunoglobulin alterations were modulated after supplementation of aqueous extract of Tinospora cordifolia (5mg/100g b.wt./day) due to antistress and antioxidant defense mechanism against toxic action of SO2 gas inhalation.