APOLIPOPROTEINS IN CAD OUR EXPERIANCESUDARSHINI RAO, SHAHEENA BANU AND B. HARISH RAO
Background - Lipoproteins are closely related to arteriosclerosis leading to coronary artery disease, hence the factors affecting lipoprotein levels are 208) and Group 3-CAD patients with diabetes (n=222). The ratio of Apo B to Apo A-I were 0.73 + 0.9, 1.4 + 1.5 and 1.7 + 1.4 in Group 1,2 and 3 respectively The concentrations of Apo B were 98 + 22.4, 138.08 19.3, and 162.0 + 16.8 mg/di in Group 1,2 and 3 respectively and ApoA-I were 133.4 + 23.1, 99.4 + 12.3, and 94.3 + 11.2 mg/d1 in group 1,2 and 3 respectively. Three groups of patients were studied with Group 1- healthy controls (n=190), Group 2- CAD patients without diabetes (n= apolipoprotein is an integral part of lipoproteins and would be useful in assessing the risk of CAD. The data suggests that Apo B is the most reliable parameter in comparison to LDL-Cholesterol and Apo B to Apo A-I ratio being the good predictor of CAD risk. Thus the study on important for better management of CAD .We investigated the role of Apo-B by Apo A-I ratio, Apo A-I and Apo B in CAD patients.
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