ANTIMICROBIAL ACTIVITY OF PASSIFLORA FOETIDA LEAF EXTRACT ON HUMAN PATHOGENSSANTH RANI THAAKUR, C. MONIKA, SANDHYA RANI BODDU AND A. KRISHNA VENI
The aim of this study was to evaluate the antimicrobial activity of Passiflora foetida, a folklore medicinal plant. Plants used for traditional medicine contain a wide range of substances that can be used to treat chronic as well as infectious diseases. Passiflora foetida is a plant that is used in traditional medicine for the treatment of eczema, eye inflammations, kidney problems, measles, prickly heat, rashes, skin ulcers, urinary burnings and wounds. Alcoholic extract of leaves of Passiflora foetida (Passifloraceae) obtained by maceration was screened for their antimicrobial activity. The extract was tested against 8 different species (Gram positive microorganisms: Bacillus subtilis, Bacillus megaterium and Staphylococcus aureus; Gram negative microorganisms: Pseudomonas aeruginosa, Pseudomonas fluorescens, Salmonella Paratyphi B., Salmonella typhimurium and Proteus mirabilis) of human pathogenic bacteria by broth dilution method and the agar well diffusion method. The plant extract showed the antibacterial activity against all the eight microorganisms. The lower concentrations of Passiflora foetida possessed similar inhibitory effect against all the test organisms. The lowest MIC values (0.5mg/mL) of alcoholic extract were against S.typhimurium and S.paratyphi B. suggesting that the alcoholic extract was most effective against S.typhimurium and S.paratyphi B. The results indicated that the alcoholic extract was found to be more effective against gram -ve microorganisms than gram +ve microorganisms.
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