Ecology, Environment and Conservation Paper

MODULATORY EFFECT OF VITAMIN E AND C AGAINST MOSQUITO COIL SMOKE INDUCED ALTERATIONS IN SERUM ENZYMES IN MALE ALBINO RAT

Asha Agarwal, Surbhi Varma and Rajni Singh

Abstract

Present study is undertaken to investigate the effect of antioxidant vitamin E and C on serum enzymes viz. alkaline phosphatase (SALP), glutamic oxaloacetic transaminase (SGOT) and glutamic pyruvate transaminase (SGPT) in mosquito coil (brand Mortein) smoke exposed albino rats. An increase in SALP (P<0.001), SGOT (P<0.001) and SGPT (P<0.001) has observed after inhalation of mosquito coil smoke in rats. After pre-exposure supplementation of vitamin E and C individually and in combination, a significant decrease in serum enzyme activity is reported. Vitamin E and C in combination have more potential effect in mitigating toxic effects of mosquito coil smoke in comparison to vitamin E and C taken alone, as vitamin E and C both work together in synergistic manner and enhance the level of antioxidant defense mechanism.