MODULATORY EFFECT OF VITAMIN E AND C AGAINST MOSQUITO COIL SMOKE INDUCED ALTERATIONS IN SERUM ENZYMES IN MALE ALBINO RATAsha Agarwal, Surbhi Varma and Rajni Singh
Present study is undertaken to investigate the effect of antioxidant vitamin E and C on serum enzymes viz. alkaline phosphatase (SALP), glutamic oxaloacetic transaminase (SGOT) and glutamic pyruvate transaminase (SGPT) in mosquito coil (brand Mortein) smoke exposed albino rats. An increase in SALP (P<0.001), SGOT (P<0.001) and SGPT (P<0.001) has observed after inhalation of mosquito coil smoke in rats. After pre-exposure supplementation of vitamin E and C individually and in combination, a significant decrease in serum enzyme activity is reported. Vitamin E and C in combination have more potential effect in mitigating toxic effects of mosquito coil smoke in comparison to vitamin E and C taken alone, as vitamin E and C both work together in synergistic manner and enhance the level of antioxidant defense mechanism.
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