Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

HEMATOTOXICITY EFFECT OF CADMIUM IN CANCEROUS WISTAR RATS

G. REVATHI, P. SUVARNALATHA DEVI, N.D. PRASANNA, P. JAYALAKSHMI, S.K. SHAHEEN AND B.R. NAIK

Abstract

Cadmium is designed as The dissipated element because of its potential for uncontrolled widespread introduction into the environment (Fulkerson et al., 1973). Cadmium toxicity depends on the dose, the route of administration, and duration of exposure. Cadmium causes renal failure by tubular and glomerular damages in kidney. This changes effects the alterations in RBC, WBC, Haematocrit and hemoglobin. The sub cutaneous injection of Wistar rats with 16μM Cadmium chloride (CdCl2) leads to the significant increase levels of RBC (F=123.61), WBC (F=99.78), Haematocrit (F=248.33) and hemoglobin (10.871). The alterations in the blood indicate the hematotoxicity of cadmium.