Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 10, Issue 3, 2008; Page No.(655-660)

AGE SPECIFIC FIATORIDE EXPOSURE IN DRINKING WATER- A CLINICAL MULTIPARAMETRIC STUDY

SHASHI, A. AND KUMAR, M

Abstract

Blood samples were collected from 145 subjects including 103 patients of skeletal fluorosis in the age group of 20-80 years from Sangrur District of Punjab, India where the concentration of fluoride in drinking water varies from 2.3 to 22.5 mg/L. The serum was analyzed for cholesterol, low density lipoprotein, high density lipoprotein, triglycerides, glucose and electrolytes and compared with controls. The results showed elevated levels of sodium and potassium ions, which indicate electrolyte imbalance and impairment of kidney function. Serum potassium level exhibited significant rise in all age groups except 20- 30 years. The levels of cholesterol, low density lipoprotein and high density lipoprotein revealed a significant decline, v■Thile there was increase in the serum triglyceride levels in the patients of skeletal fluorosis in all age groups. Serum glucose levels decreased in the fluorotic patients in comparison to control indicating hypoglycemic condition.

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