Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 10, Issue 3, 2008; Page No.(639-644)

PATHOLOGY AND CLINICAL ASPECT OF AUTOIMMUNE THYROIDITIS AND ON-AUTOIMMUNE THYROID DISEASE

SHASID, A. AND KAUR, V.

Abstract

The clinicpathological study was carried out in 105 cases of thyroid disorders coming for the treatment in the OPD's of Department of Endocrinology, Government, Rajindra Hospital, Patiala, India. The age range was from 8 to 68 years with maximum number of cases in the age group 20-40 years (50.47%). The peak incidence was in the fourth decade of life (27.61%), 78% were females and 22% were males thereby showing female preponderance in thyroid disorders in present study. The metabolic lesions of thyroidism (80.95%) predominated in the studied population followed by non-neoplastic (16.19%) and neoplastic lesions (2.85%). The pathologies included toxic goiter (4.76%), Hashimoto's thyroiditis (2.85%), Riedel's thyroiditis (1.90%) and thyroid adenoma (2.85%) in female patients. There was histopathological evidence of scalping of colloid, infiltration of chronic inflammatory cells, extensive fibrosis and formation of fibrous capsule, compressed glandular tissue and distorted follicles.

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