Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 10, Issue 3, 2008; Page No.(547-550)

RESPONSES OF CYPERMLTHRIN INTOXICATION-INDUCED STRESS IN HAEMATOLOG TCAL PROFILES OF MAMMALIAN MODEL ALBINO RAT

A. NAGARJUNA, S. RAJENDRA PRASAD, S. SIRAJ MOHIYUDDIN, R. JAYA KUMAR, Y. SAVITHARI AND P. JACOB DOSS

Abstract

Cypermethrin is. a synthetic pyrethroid that belongs to a group of insecticides with low mammalian toxicity but high insecticidal activity. On exposure to sublethal doses of cypermethrin the haematological parameters were investigated in different groups of albino rats [single, double and multiple doses (41, 82 and 164 mg/kg body weight)]. The pesticide was administered orally by gavage method with an interval of one day. The results revealed statistically significant decrease of RBC, Hb, PCV, MCV, MCH, MCHC, neutrophils and increase of WBC, lymphocytes and monocytes.

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