ETIOPATHOGENESIS OF HAEMOLYTIC ESCHERICHIA COLI ISOLATED FROM PREGNANT WOMEN WITH URINARY TRACT INFECTIONC. DHARANI , K. ARUNJUNAI RAJAN, S. ARJUNAN AND S. KANNANAbstract Urine samples collected from 75 antenatal women were screened for asymptomatic bacteriuria. Out of them 20% (15 samples) were culture positive. The uropathogenic isolates include Escherichia coli, Proteus spp, Klebsiella spp and Staphylococcus spp. Escherichia coli was the predominant species among the identified (8/15) bacteria and among them, 25% showed haemolysis on blood agar. The haemolytic Escherichia coli injected transurethrally into the pregnant mice showed inflammation in kidney. The haemolytic Escherichia coli was found to be sensitive to the antibiotics viz., Nalidixic acid, Trimethoprim, Ofloxacin, Ciprofloxacin and Kanamycin. The organism was resistant to the antibiotics viz., Rifampicin, Amikacin, Ampicillin and Carbenicillin.
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