Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 9, Issue 3, 2007; Page No.(645-648)

SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF ISATIN-3- SEMICARBAZONE AND SUBSTITUTED ISATIN-3- SEMICARBAZONE

S. N. PANDEYA, ALKA PANDEY, R. L. GUPTA2 AND KISHU TRIPATHI

Abstract

Isatin-3-semicarbazone and substituted Isatin-3-semicarbozone were synthesized and their antibacterial activity was screened.It was observed that chloro (II-2) , methoxy(II-6) , bromo (II-4) and nitro(II-5) substituted Isatin-3-semicarbazone exhibited activity against more than 50% of bacteria .Among the series ,the least active was the compound with methyl substituent(II-3)

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