CLINICO-MYCOLOGICAL PROFILE AND INVITRO SENSITIVITY OF SUPERFICAL MYCOSIS IN JABALPUR, CENTRAL INDIANAMITA GROVER BEDI, SAKSHI DIXIT, SR NAWANGE, NEELIMA RAIPURIA AND RANI SHUKLA
A clinicomycological study of superficial mycoses and in vitro sensitivity of fluconazole, griseofulvin and clotrimazole was conducted against the clinical isolates of superficial mycosis during 4 month study period in Jabalpur central India. Direct microscopy by KOH mount and culture was undertaken to isolate the fungal pathogen in each case. Dermatophytosis was the commonest fungal infection in (70%) of positive cases followed by candidiasis (10%), P. versicolor (5%) and nondermatophyte infection (15%). The species of dermatophytes isolated were Trichophyton verrucosum, Microsporum persicolor, Microsporum audouinii, Trichophyton mentagrophytes, T. terrestre, T. rubrum and Malassezia ovalis. The commonest dermatophytosis were Tinea pedis (35.7%), Tinea unguium (28.57%), Tinea corporis (14.28%) , Tinea capitis (14.28%), Tinea manuum (7.1%). The commonest Nondermatophyte molds isolated were Aspergillus flavus (5%), Penicillium chrysogenum (5%) and Alternaria alternata (5%). In vitro antifungal activity of fluconazole, griesofulvin and clotrimazole were tested against the clinical isolates of superficial mycosis and all the three drugs have shown good susceptibility pattern against the genus Trichophyton and Microsporum.
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