ANTI-DIABETIC AND ANALGESIC ACTIVITY OF LEAVES OF ABUTILON INDICUMD. M. SARKAR, U. M. SA RKAR, N. M. MAHAJANAbstract The leaves of Abutilon indicum Linn. were traditionally used to treat bronchitis, gonorrhoea, and as mouthwash in toothache, etc. The plant of Abutilon indicum is available in reach source at Melghat tiger reserve forest area. The tribal community living in-the Melghat forest used abudlon indicum leaves to control diabetes mellitus. Hence, the present study was planned to verify this claim and also to screen for the analgesic property. In addition, an attempt was made to identify the class of phytochemicals present in the leaves and also attribute the pharmacological property of the leaves to the particular type of phytochemicals. The results revealed that the leaves contain steroids, sapogenins, carbohydrates and flavonoids. It was also observed that different extracts have shown significant hypoglycemic activity at 400 mg/kg dose, but aqueous extract was most potent in reducing the blood glucose levels. Similarly petroleum ether extract and benzene extract were found to possess very good analgesic property. In addition all the extracts have shown CNS depressant activity. The results revealed that the use of leaves in controlling diabetes mellitus is justifiable.
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