Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 8, Issue 3, 2006; Page No.(581-584)

RAPID SCREENING AND CONFIRMATION OF ASPERGILLUS TERRELIS STRAINS FOR L-ASPARAGINASE PRODUCTION

K. LIN GAPPA AND K. G. SIDDALINGESHWAR

Abstract

Studies were under taken on Aspergillus terreus to evaluate their ability to produce Lasparaginase-an antitumor agent through plate assay method. In the present study A. terreus KLS2 exhibited maximum zone. The isolates which exhibited max zones were employed for solid state fermentation for L-asparagina se production. The values obtained by plate assay method indicated positive correlation between zone of diameter and L-asparaginase production and reveals that plate assay method can be used for rapid screening of L-asparaginase producers.

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