Ecology, Environment and Conservation Paper

BIOSYNTHESIS OF NICKEL OXIDE NANOPARTICLES USING DELONIXELATA EXTRACT FOR ANTICANCER ACTIVITY

V. Shanmugapriya and S. Suguna

Abstract

Biosynthesis of nanoparticles has recently gained the attention of scientists because of the necessity to discover new techniques of synthesis that are safe, cost-effective and dependable. In a wide range of applications, metal oxide nanoparticles are increasingly gaining interest in particular. In this research, we produced NiO nanoparticles by green technology utilising Delonixelata extract, a natural non-toxic hydrocolloid and explored its potential antibacterial, anticancer and antioxidant use. The biosynthesized nickel oxide nanoparticles (NiO) were studied by Scanning electron microscopy (SEM), X-ray diffraction (XRD), and UV-visible spectroscopy. The findings revealed that NiO nanoparticles produced from Delonixelata exhibited better anticancer activity against renal cancer cell line (ACHN). An in vitro cell assay showed that NiO nanoparticles were significantly cytotoxic against the renal cancer cell line (ACHN).