Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 04, Issue 1, 2002; Page No.(15-20)

STUDIES ON THE METABOLISM OF CATECHOLAMINES IN CHLORPYRIFOS TREATED RATTLIS NORVEGICLIS WITH CHALLENGES OF DRUGS

KARUNAKARAN AND S. DURAIRAJ

Abstract

Catecholamines such as dopamine, nor - epinephrine and epinephrine at different intervals were analyzed in the brain regions of chlorpyrifos treated Rattus norvegicus and the catecholamine levels mimic the extrapyramidal symptoms like parkinsonism. However, the levels of catecholamine were restored significantly as that of control due to atropine, pyridine aldoxime methiodide, reserpine and propranolol treatment over a period of 24 h.

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