Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol. 24, Issue 4, 2022 ; Page No.(751-756)

A SPECTRUM OF BACTERIAL SEPSIS IN COVID -19 POSITIVE AND NON COVID -19 PATIENTS – AN INDIAN MONOCENTER RETROSPECTIVE STUDY

R. PREETHY, U. SUNDERESH KAMAL CHANDER, D. ARUNA, MUTHUVEL E. AND SONTI SULOCHANA

Abstract

This study aims to determine spectrum of bacterial infection in patients with severe acute respiratory syndrome coronavirus-2 infection at the time of hospital admission and identify changes in hematological biomarkers of COVID19 severity. A retrospective study was conducted in blood cultures from patients suspected to have sepsis were included in the study. Patients were grouped based on SARS-CoV-2 RT-PCR result as positive, negative, or not tested. For the purposes of classifying blood cultures by SARSCoV- 2 RT-PCR status, hematological parameters were analyzed. Out off 825 blood sample, 466 samples was positive for blood culture identified by conventional and Automatic blood culture system – Vitek 2. Among these 466 patients, 211(45.2%) were positive for SARS-CoV2 virus and 255 (54.7%) were negative for SARSCoV2 virus by RT -PCR. Regarding CRP Total number of CRP positive samples was 654, CRP negative samples was 84 and CRP was not done for 87samples. The total number of IL6 positive samples was 83 and IL6 negative samples were not evaluated for 125 patients. The concern of Bacterial sepsis in COVID-19 patients due to the above organisms based on our study over the period of one year. Consequently, it is important to pay attention to bacterial co-infections in critical patients diagnosed for COVID-19.