Pollution Research Paper

Vol.30, Issue 3, 2011; Page No.(289-292)

PROTECTIVE EFFECTS OF VITAMIN E AND C ON SERUM ENZYME ACTIVITY IN SULPHUR DIOXIDE EXPOSED RATS

ASHA AGARWAL AND DEEPTI BAGHEL

Abstract

The present study was designed to assess the combined effects of vitamin E and C supplementation on sulphur dioxide induced alterations in serum enzyme activity in wistar albino rats. The rats of both the sexes were exposed to 80ppm of sulphur dioxide gas for 28 days with preexposure supplementation of vitamin E (0.1 mL/100g b.wt.) and vitamin C (0.2 mL/100g b.wt.) in combination. A significant decrease in serum alkaline phosphatase (SALP), serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) after supplementation of vitamin E and C in combination in comparison to sulphur dioxide gas exposed rats is due to hepatoprotective role of vitamin E and C in combination against sulphur dioxide induced toxicity.

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