Ecology, Environment and Conservation Paper

IN VITRO ANTHELMINTIC ACTIVITY OF MEDICINAL PLANT TINOSPORA CORDIFOLIA EXTRACT ON AMPHISTOME GASTROTHYLAX CRUMENIFER

Babita Jogpal, Gayatri Swarnakar, Hitendra Singh Chouhan and Kiran Roat

Abstract

In vitro anthelmintic activity of medicinal plant Tinospora cordifolia extracts was studied on the amphistome Gastrothylax crumenifer parasites. Live amphistome Gastrothylax crumenifer were collected from the infected rumen of freshly slaughtered domestic Goat at the local meat market of Chittorgarh (Raj.). The anthelmintic effects of different concentration of albendazole, alcoholic and aqueous stem extract of T. cordifolia against G. crumenifer were studied. High concentration of albendazole of 100 mg/ml showed 72% mortality rate after 5 hours of exposure on G. crumenifer. The aqueous extracts of T. cordifolia showed highest mortality rate of 100% at concentration of 100 mg/ml after 5 hours of exposure time. Whereas, the highest mortality rate of 100% was observed with alcoholic extracts at 100 mg/ml of concentration in 4 hours exposure time. The study revealed that alcoholic and aqueous extracts of T. cordifolia caused more mortality compared albendazole. The alcoholic extract was highly potent than aqueous extract of T. cordifolia. The present study will improve the socio-economic condition of the Goat farmers of Chittorgarh (Raj.) by removing pathogenic amphistome G. crumenifer parasites with the treatment of medicinal plants T. cordifolia.