Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 14, Issue 3, 2012; Page No.(375-379)

ANTIBIOTIC SUSCEPTIBILITY OF BACTERIAL PATHOGENS ISOLATED FROM DIABETIC PATIENTS

V. RAJALAKSHMI AND V. AMSAVENI

Abstract

Diabetic foot wounds are a major complication of diabetes resulting in substantial morbidity and mortality due to a mixture of aerobic and anaerobic organisms. The present study evaluates the necessity of screening the bacterial pathogen in time and to determine the antibiotic susceptibility of the suspected organisms, so as to help identify an empirical therapy. This reduces the consumption of wide spectrum of antibiotics which in turn forestalls a wide spectrum of side affects and thus saves the diabetic victims from the extremity amputations. The study aims to screen the bacterial pathogens present in diabetic pus and to determine their antibiotic sensitivity and resistance pattern against the recently used standard antibiotics (Amikacin (30 [ig), ampicillin (10 tig ), cefotoxime (30[1g), ceftazidime (30t_tg), cefazolin (30t_tg), ceftriaxone (30 ig), ciprofloxacin (10 ig), gentamycin (10 ig), imipenem (10 ig), ofloxacin (5 ig), penicillin - G (2 ig), piperacilin (100) tig, sulphamethazole (10 [ig), trimethoprim (10 ig), vancomycin (30 tdg). The common pathogens isolated from the diabetic pus include Gram positive bacilli like (Staphylococcus aureus, Streptococcus pyogens, and Gram negative bacilli like Pseudomonas aeruginosa, Escherichia colt, Klebsiella sp. and Proteus sp.).

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