Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 22, Issue 4, 2020; Page No.(642-647)

IN VITRO SUSCEPTIBILITY TESTING OF INDOOR FUNGI BY ETEST

ANIRBAN CHAUDHURI, SUBARNA BHATTACHARYYA AND PUNARBASU CHAUDHURI

Abstract

Antifungal susceptibility tests have become important tools to guide the treatment of invasive fungal infections and also to detect antifungal resistance. Susceptibilities to antifungal drugs were determined by Etest for 50 isolates from indoor environments. Growth inhibition ellipses were uniform and well-delineated, and the points of intersection with the Etest strips were clearly determined after 48 h of incubation at 27 oC. According to the obtained results, all strains were found to be resistant to Fluconazole, whereas Aspergillus sp. was most susceptible for Posaconazole and Itraconazole antifungal agent. 90% of isolates were susceptible to Posaconazole and Itraconazole. In the present study, Posaconazole and Itraconazole were the most effective drugs for all isolates. Determining the susceptibility pattern is mainly required to assist clinicians in treating most superficial dermatophyte infections more effectively.

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