NOVEL CORONA VIRUS (COVID-19) OUTBREAK - A REVIEWASHWITHA K., WASEEQUR RAHMAN MD, RANJITH SIVA K., SURESH BABU B. AND KALYANI C.H.Abstract Coronavirus disease 2019 (COVID-19) represents a significant and urgent threat to global health and is a respiratory tract infection caused by a newly emergent coronavirus, SARS-CoV-2 with mild to severe outcomes. Genetic sequencing of the virus suggests that SARS-CoV-2 is a beta coronavirus closely linked to the SARS virus. Recent studies have begun to reveal some fundamental aspects of the complicated host- HCoV interaction, multiplication, epidemiology, symptoms and possible treatments in detail. In this review, we recapitulate the current knowledge of types of signalling mechanisms and pathways opted by the virus during HCoV infection, with emphasis on genetics, epidemiology, routes of transmission, its comparison with other flus, statistical data of the confirmed cases, and precautions. The cross talk among the vaccinations is also discussed. |