THE CHARACTERIZATION OF TOMATO JUICE PATCH AS DENTAL BLEACHING WITH HPMC-PVP COMBINATION POLYMER BASEB. NOVIANITA, L. HENDARMIN AND Y. ANGGRAENIAbstract Natural dental bleaching has been used as an alternative to avoid the risk of irritation due to the application of dental bleaching made from peroxide groups. Tomato has known to have good potency in teeth whitening. Dental bleaching also has various dosage forms and the patch is one of the most-preferable dosage forms because of its convenience when it is applied. In this research, a tomato (Solanum lycopersicum L.) juice patch has been established as a natural dental bleaching product. The objective of this research was to characterize the tomato juice patch with Hydroxypropylmethylcellulose (HPMC) and Polyvinylpyrrolidone (PVP) combination polymeric-base. Patches were formulated in three formulas by varying the tomato juice concentration into 55%; 60%; and 65% (w/w). Patches were prepared with the solvent casting method. Patch characterization has shown the results that all formulas have thicknesses in the range 100-300 μm; pH in range 4-5; folding endurance >300 times; and can be attached to teeth specimens for more than 3 hours. |