EFFECT OF NICKEL CHLORIDE ON LACTATE DEHYDROGENASE ACTIVITY IN SELECTED TISSUES OF FISH LABEO ROHITA (HAMILTON)K. Moorthikumar, A. Krishnamoorthi and M. MuthulingamAbstract Lactate dehydrogenase (LDH) is the glycolytic enzyme affected by the toxicity of heavy metals. The aim of the present study is to determine the activity of lactate dehydrogenase in gill, liver, kidney, brain and muscle of the fish, Labeo rohita exposed to sublethal concentrations of nickel chloride 1/15th (low) 1/10th (medium) and 1/5th (high) of the 96 hours values for the period of 10, 20 and 30 days. The activity of lactate dehydrogenase was significantly (P<0.05) decreased in gill, liver, kidney, brain and muscle of the fish, Labeo rohita. Therefore, the effect of nickel chloride have deleterious effect on the activity of lactate dehydrogenase in selected tissues of Labeo rohita as revealed in this investigation. |