PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL PROPERTY OF LEAVES OF POGOSTEMON BENGHALENSIS (BURM. F.) KUNTZESWATI LODHA AND SANJAY DESHMUKHAbstract Department of Life Sciences, Mumbai University, Santacruz (E), Mumbai 400 098, Maharashtra, India. Phytochemical analysis and antimicrobial property of Pogostemon benghalensis leaf was studied. The cold extracts of leaf were prepared in acetone and methanol solvents. The phytochemical analysis of bioactive acetone and methanol extract was carried out. The phytochemical analysis of different solvent extract of this plant showed the presence of different classes of metabolites such as alkaloids, flavonoids, tannins, steroids, saponins glycosides, carbohydrates and proteins. Agar cup technique was used to assess the antimicrobial activity of acetone and methanol leaf extracts against five human pathogenic bacteria strains (Staphylococcus aureus, Streptococcus faecalis, Pseudomonas aeruginosa, Streptococcus pyogenes, Bacillus subtilis). The acetone leaf extract showed antimicrobial activity against all the organisms expect for B. subtilis as compared to methanol leaf extract. The minimum inhibitory concentration was 12.5 mg/mL in acetone extract. The present study gives an insight for further phytochemical and pharmacological investigation of this plant. |