Asian Journal of Microbiology, Biotechnology & Environmental Sciences Paper

Vol 21, Issue 4, 2019; Page No.(862-864)

PITUITARY ACTH-DEPENDENT CUSHING’S SYNDROME, A CASE REPORT

HARI HENDARTO AND FEMMY NURUL AKBAR

Abstract

Cushing’s disease is a rare disease that is caused by the overproduction of cortisol caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma. The diagnosis for Cushing’s disease is made by laboratory testing, which demonstrates the supraphysiological levels of circulating cortisol. Magnetic Resonance imaging (MRI) enhances detection of ACTH-secreting pituitary adenomas. If left untreated, an ACTH-secreting pituitary adenoma often results in diminished patient survival and worsened quality of life. Early diagnosis and appropriate treatment can reverse the signs and symptoms and leads to a significantly improved quality of life. Here we present a case report of a young obese female with diagnosis of pituitary ACTH-dependent Cushing’s syndrome.

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